Bile Acids and Steroids
نویسندگان
چکیده
منابع مشابه
Bile Acids and Steroids
In several mammalian species, i.e. rabbit, dog and man, deoxycholic acid is one of the main bile acids in the bile (1). In recent years evidence has accumulated that deoxycholic acid is formed from cholic acid during the enterohepatic circulation by the action of intestinal microorganisms. By the use of 24-@-labeled cholic acid this conversion has been demonstrated in rabbit and in man (2,3). B...
متن کاملSteroids Derived from Bile Acids
Derivatives of bile acids with substituents in Ring C have been described in the preceding papers of this series (l-6). It is the purpose of this paper to assign the probable stereochemical configurations for these compounds. As desoxycholic acid (I)l is a convenient reference compound, it will first be necessary to discuss briefly the spatial arrangement of certain portions of this bile acid. ...
متن کاملContraceptive steroids alter the steady-state kinetics of bile acids.
Contraceptive steroids increase the ratio of cholic acid to chenodeoxycholic acid in bile. This alteration may contribute to the development of cholesterol gallstones. The objective of this study was to measure the effects of contraceptive steroids on bile acid kinetics and to relate them to changes in cholesterol metabolism. Steady-state kinetics of bile acids were measured in 15 healthy women...
متن کاملBile Acids and Steroids LXXXIII. ON THE IKTERCONVERSION OF CHOLIC AND DEOXYCHOLIC ACID IN THE RAT
Cholic acid and chenodeoxycholic acid are the main bile acids in rat bile, occurring in the approximate proportion of 8:2 (1). The occurrence of minor amounts of metabolites of cholic and chenodeoxycholic acid, formed by the action of intestinal microorganisms and liver enzymes, has recently been reported (2, 3). The transformation of labeled cholic acid during the enterohepatic circulation has...
متن کاملBile acids and steroids. LXXXII. On the mechanism of deoxycholic acid formation in the rabbit.
In several mammalian species, i.e. rabbit, dog and man, deoxycholic acid is one of the main bile acids in the bile (1). In recent years evidence has accumulated that deoxycholic acid is formed from cholic acid during the enterohepatic circulation by the action of intestinal microorganisms. By the use of 24-@-labeled cholic acid this conversion has been demonstrated in rabbit and in man (2,3). B...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1959
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)69861-8